Methyl 1-benzyl-3-pyrrolidinecarboxylate

Methyl 1-benzyl-3-pyrrolidinecarboxylate - Names and Identifiers

Name	METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE
Synonyms	Methyl 1-benzyllpyrrolidi... METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE METHYL 1-BENZYLPYRROLIDINE-3-CARBOXYLATE Methyl 1-benzyl-3-pyrrolidinecarboxylate Methyl 1-benzyllpyrrolidine-3-carboxylate 1-Benzyl-3-pyrrolidinecarboxylic acid methyl ester 1-BENZYL-PYRROLIDINE-3-CARBOXYLIC ACID METHYL ESTER 3-Pyrrolidinecarboxylic acid, 1-(phenylMethyl)-, Methyl ester
CAS	17012-21-4
InChI	InChI=1/C13H17NO2/c1-16-13(15)12-7-8-14(10-12)9-11-5-3-2-4-6-11/h2-6,12H,7-10H2,1H3

Methyl 1-benzyl-3-pyrrolidinecarboxylate - Physico-chemical Properties

Molecular Formula	C13H17NO2
Molar Mass	219.28
Density	1.08
Boling Point	98℃/0.2mm
Flash Point	104.792°C
Water Solubility	Sparingly soluble in water.(0.26 g/L) (25°C),
Vapor Presure	0.002mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Light orange to Yellow
pKa	8.34±0.40(Predicted)
Storage Condition	2-8°C
Refractive Index	1.5211
MDL	MFCD04038678

Methyl 1-benzyl-3-pyrrolidinecarboxylate - Introduction

METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE, also known as BPMAC or N-Boc pyrrolidine-3-carboxylic acid METHYL ester, is an organic compound. Its chemical formula is C13H15NO3 and its relative molecular mass is 229.26.

METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE is a colorless liquid with a fragrant Ester odor. It is latent cold soluble in a variety of organic solvents, such as ethanol, chloroform and dimethylformamide. The compound is relatively stable in the environment, but it has the risk of burning when encountering high temperature, open flame and other ignition sources.

METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE is commonly used as an organic synthesis intermediate. It can be used in protein synthesis, pharmaceutical synthesis and other fields. Specific uses include industrial synthetase inhibitors, pharmaceutical intermediates, and the like.

There are many methods for preparing this compound, one of the common methods is obtained by N-protection of pyrrolidine and esterification under acid catalysis. First, pyrrolidine is esterified with methanol to obtain methyl formate of pyrrolidine. The resulting product is then reacted with benzyl alcohol to give METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE.

Regarding safety information, METHYL N-BENZYL-3-PYRROLIDINECARBOXYLATE is a combustible material and can aggravate a fire. Care should be taken to avoid contact with skin, eyes and respiratory tract and to maintain good ventilation during handling and use. In addition, it should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 21:01:54